Molecular pharmacological studies on the mechanisms of action of tumor promoter phorbol esters
نویسندگان
چکیده
منابع مشابه
Epigenetics of Phorbol Esters, a Tumor Promoter and Differentiation Inducer
Epigenetics is the study of structurally and functionally relevant molecular changes to the genome that do not constitute a change in the nucleotide sequence such as DNA methylation and histone modifications. These changes are involved in the expression and repression of different genes in a particular cell type. Phorbol esters are diterpene compound known as phorbol 12-myristate 13-acetate (PM...
متن کاملTumor-promoting Phorbol Esters
The effect of tumor-promoting phorbol esters on the in vitro proliferation of mouse pluripotent hematopoietic stem cells (CFU-S) was examined using a short-term in vitro culture system and an 11-d spleen colony assay. Phorbol myristate acetate (PMA, 10-7 M), but not the inert compound phorbol, supported the in vitro survival of day 11 CFU-S for 72 h in a manner similar to IL 3. PMA also enhance...
متن کاملanalysis of reading comprehension needs of the students of paramedical studies: the case of the students of health information management (him)
چکیده ندارد.
15 صفحه اولthe effect of taftan pozzolan on the compressive strength of concrete in the environmental conditions of oman sea (chabahar port)
cement is an essential ingredient in the concrete buildings. for production of cement considerable amount of fossil fuel and electrical energy is consumed. on the other hand for generating one tone of portland cement, nearly one ton of carbon dioxide is released. it shows that 7 percent of the total released carbon dioxide in the world relates to the cement industry. considering ecological issu...
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ژورنال
عنوان ژورنال: Japanese Journal of Pharmacology
سال: 1988
ISSN: 0021-5198
DOI: 10.1016/s0021-5198(19)56981-5